Make a template (or use the one provided with the drain assembly) and use it to draw a circle sized to fit the drain. Be sure the circle is centered at the low point of the bottom of the bowl or vessel to ensure proper drainage. Double check your marks and measurements before cutting. Since the faucet sits outside the sink there is no need to cut holes for it in the bowl or vessel.
Put on safety goggles. Carefully drill a starter hole inside the circle drawn on the vessel, large enough for the diamond Sawzall blade to enter. Carefully cut out the opening with the saw.
Press plumber’s putty around the flange of the drain, fitting it into drain hole (from the inside of the bowl or vessel). Secure with a rubber gasket and large nut on the back side. The sink is ready for installation.