Wood Knobs
Step 1
Remove the stripped-out wooden knob and the metal knob screw with a screwdriver. If the knob is large and deep, reattach it to the wooden drawer with a metal screw 25 to 50 percent longer than the original.
Step 2
Dip three or four wooden toothpicks into wood glue and stick them into the screw hole of the wooden knob if the knob is too small and shallow to accept a longer screw. Use enough toothpicks to fill the hole. Cut off the protruding ends of the toothpicks with a utility knife so they are flush with the knob’s wood. Wipe excess glue from the knob.
Step 3
Place the repaired wooden knob on the outside of the wooden drawer over the screw hole, and push the metal knob screw through the hole from the inside. Hold the knob in place with your hand while you drive the screw into the toothpicks lining the knob screw hole until the screw is tight.
Metal Knobs
Step 1
Remove the metal knob from its screw, leaving the screw in place.
Step 2
Coat the exposed end of the screw with a liquid thread-locking adhesive compound.
Step 3
Thread the knob onto the screw and tighten the connection with a screwdriver until it's as snug as possible; tightening too much likely will cause the threads to slip, loosening the knob. Allow the knob to sit overnight before using the drawer.