Clean the granite countertop around the drain hole cutout and any other area where the sink will be making contact with a granite cleaner. Spray the cleaner directly on the stone and buff it dry with an absorbent cloth.
Place the vessel sink onto the counter and line it up with the drain cutout. Check to see how much of the sink will be in contact with the granite, and find the exact position you want the sink to be in. Remove the sink and set it aside.
Squeeze the tube of silicone adhesive directly onto the granite around the drain cutout. If the sink will be making contact with the granite in other areas, apply additional adhesive to those parts.
Lift the sink back into place and settle it onto the granite. Line it up with the drain cutout. Let the adhesive harden overnight.
Drop the tail end of the drain through the top of the sink. Tighten the tail below the granite counter while holding the sink in place. Attach the drain tail to the waste pipe.