Vacuum the exterior of the purifier unit with the vacuum cleaner's brush attachment, focusing on the air intake and outlet vents. Wipe down the exterior with a well wrung, slightly damp rag sprayed with surface cleaner or a premoistened household cleaning wipe, such as Clorox wipes.
Remove the pre-filter and HEPA filter from the purifier casing. Vacuum around each well and replace the pre-filter over the HEPA filter if needed.
With the filters removed, vacuum out the interior of the purifier unit thoroughly with the brush and crevice attachments. Pay special attention to the intake and outflow vents where significant debris can get lodged. Wipe down the interior with a slightly dampened rag sprayed with surface cleaner or a premoistened wipe to pick up any remaining dust and debris and to disinfect the interior surface.
Replace the HEPA and pre-filters into the unit and secure the unit casing. Plug the unit back into the power supply and turn it on to test for smooth operation.